The cyberdemon's first chronological appearance (in-universe) is in Wolfenstein RPG, where it appears fully organic as the Harbinger of Doom, summoned by the Nazis at Castle Wolfenstein during World War II.

In the action role-playing game Doom RPG, the Cyberdemon is created by an occultist scientist Kronos. As with many of the returning demons in Doom Eternal, the Tyrant has been redesigned from its Doom (2016) incarnation to more closely resemble its design from the original Doom games. In Doom Eternal an iteration of the Cyberdemon appears as a mini-boss under the name Tyrant. Also, at the start of each ball, the player is challenged to launch the ball past the Cyberdemon's arm cannon attacks to pull off a skill shot. It serves as the final boss of the 2016 reboot's virtual pinball adaptation (instead of Olivia Pierce, that game's main antagonist), whom the player can fight after fulfilling certain conditions, or by triggering wizard mode by completing five main missions.

Another incarnation of the Cyberdemon appears as a boss in the 2016 reboot of Doom, this time depicted as an ancient demon lord reanimated and upgraded with advanced technology by the UAC, though retaining the original's susceptibility to the player's arsenal. Ī redesigned Cyberdemon is the final boss in the reboot game Doom 3, where it is described as 'Hell's mightiest warrior' and can be killed only with the Soul Cube. The Cyberdemons return in Doom II: Hell on Earth, where one is depicted on the cover art and the title screen. This walking nightmare has a rocket launcher for an arm and will definitely reach out and touch you.' In the first Doom, the Cyberdemon is the toughest character, with 4,000 hit points (an equivalent of 40 direct rocket hits), receiving no splash damage from explosions.

The manual for the console versions describes it as a 'half unfeeling machine, half raging horned devil. The Cyberdemon is not mentioned in the manual for the original PC version, possibly so as to make its appearance a surprise for the player.

How to beat the cyberdemon in doom